Ovarian cyst research paper

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Ovarian hyperstimulation occurs more often with invasive moles and choriocarcinoma than complete molar pregnancies. A widely recognised method of estimating the risk of malignant ovarian cancer based on initial workup is the risk of malignancy index RMI. The RMI is calculated as follows: [15].

Cysts associated with hypothyroidism or other endocrine problems are managed by treating the underlying condition. Functional cysts and hemorrhagic ovarian cysts usually resolve spontaneously.


Cysts that persist beyond two or three menstrual cycles , or occur in post- menopausal women, may indicate more serious disease and should be investigated through ultrasonography and laparoscopy , especially in cases where family members have had ovarian cancer. Such cysts may require surgical biopsy. Additionally, a blood test may be taken before surgery to check for elevated CA , a tumour marker , which is often found in increased levels in ovarian cancer, although it can also be elevated by other conditions resulting in a large number of false positives.

Although most cases of ovarian cysts involve monitoring, some cases require surgery. While the smaller cysts mostly disappear within 6 months the larger ones appear to be more persistent. From Wikipedia, the free encyclopedia. Office on Women's Health. November 19, Archived from the original on 29 June Retrieved 27 June The Cochrane Database of Systematic Reviews. Journal de Gynecologie, Obstetrique et Biologie de la Reproduction.

Archived from the original on 7 September Retrieved 30 August Fertility and Sterility. Authors: Nathan Webb and David Chelmow. Archived from the original on Human Reproduction Update. Journal of Pediatric and Adolescent Gynecology. A single center experience". The Journal of Obstetrics and Gynaecology Research. Archives of Gynecology and Obstetrics.

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Guideline CG Edinburgh: SIGN. Retrieved Understanding Ovarian Cyst. Archived from the original on 16 March Bluth Orshan Diseases of the Human Body. Philadelphia, PA: Library of Congress.

New study shows women with simple cysts are not at increased risk of ovarian cancer

Acta Chirurgica Belgica. Updated by: Linda J. Vorvick and Susan Storck. The two evaluated papers dealt with the histopathological examination of ovaries. The origin of the specimens examined is not specified by the authors of both publications. Hence, data on the animals, their medical history and clinical findings are not available. Blinding to the specimens or randomization was not performed. Histopathological findings and staining procedures were described in detail.

Cysts and Ovaries

Studies on ovarian cysts focusing on clinical aspects like treatment options and fertility could not be identified. Some case reports are available and are cited in the text if they contribute additional information. In the presented studies, details on the animals such as breed, reproductive history and clinical findings are not given. In addition, inconsistencies concerning clear definitions of types of the cysts, their incidence and clinical relevance can be found. For example, Dow found ovarian cysts in 90 animals of In a study on cystic ovaries by Knauf, Bostedt, Failing, Knauf, and Wehrend , the number of cysts per individual varied from 1 to Yet, this group did not determine the type of the cysts.

In most cases, ultrasonography will be sufficient to diagnose ovarian cysts. After surgical removal, ovaries showing abnormalities should be submitted to histopathological examination Dow, Also, steroid hormone concentrations in collected cystic fluid can be examined. Follicular cysts are usually thin walled, lined with a granulosa cell layer and contain a clear watery fluid. Lutein cysts are lined with luteal tissue and have thicker and opaque walls Dow, Data on breed and the reproductive history of the dogs from which specimens were retrieved are not given.

The normal corpus luteum in the dog shows central cavitation for a short time after ovulation. A persistent fluid filled cavity may indicate an incomplete luteinization and therefore is defined as cystic corpus luteum Dow, The rete ovarii tubules are remnants from embryologic structures and are located in the medulla at the hilus of the ovary. Usually, these cysts do not produce hormones. These cysts originate from the ovarian surface and may also be called germinal cysts.

These cysts are usually found by coincidence in older dogs and have no clinical relevance. However, they may communicate with the rete tubules so that both may dilate simultaneously.

Journal of Ovarian Research | Articles

Usually, these cysts have no clinical relevance. Scarce systematic research results are available with regard to treatment options, success rates and side effects of the different cysts.

The types of the cysts were not defined and a long term observation of the therapy success and possible recurrences was not performed. Because of possible side effects, especially young bitches may be considered untreated. Spontaneous regression of the cysts may occur, although no data on the percentage of spontaneous regression are available. Via CAB abstracts, 78 articles on ovarian neoplasia were identified. After excluding doublets, 53 publications remained.

Evaluation of Ovarian Cysts

According to the preset exclusion criteria, 49 articles had to be excluded, resulting in four remaining publications. In total, four publications contained case reports. The identified and evaluated papers mainly provided information on histopathological findings of canine ovaries with neoplasia. Hence, in those cases, data on the animals, their breed, age, medical and reproductive history and clinical findings are not available.

Some information about age, breed and clinical findings were recorded. In the retrospective study of Hayes and Young , records of a data collection registry used by 13 North American veterinary university hospitals were evaluated. The case report forms comprised data on age, breed, diagnostic procedures, diagnoses and surgical procedures. However, these data are not given in detail in the manuscript. Patnaik and Greenlee also performed a retrospective study of medical records.

The data originating from one hospital included information on age, breed, clinical and gross pathological findings. Data concerning breed, age and clinical findings were recorded and are presented. Specimens were collected by fine needle aspiration or laparotomy. Ultrasonography was successful in detecting the ovary as origin of the abdominal mass in eight of the ten dogs. Tumour may, however, show various patterns simultaneously.

The reported incidence of ovarian tumours ranges from 0. Hayes and Young showed that the risk for dogs to be diagnosed with epithelial and granulosa cell tumours rises with increasing age. Also, Cotchin reported an incidence of 7. Patnaik and Greenlee did not give details on the exact numbers of affected animals but compared the rate of occurrence of different breeds having ovarian neoplasia to the respective rate of occurrence of the breeds in the hospital population. According to them, Boston Terriers, mixed breeds, German Shepherds and Poodles had a higher prevalence of ovarian neoplasia compared to other breeds.

It must be considered that this kind of data collection and interpretation may be highly biased by factors like the local breed distribution, the population that is presented to a specific type of hospital or the willingness of patient owners to submit specimens for histopathological examination.

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